Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 5/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29948180 | 1.00 | SIRT1 (0.43) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL363595 | 0.82 | BCAT2 (0.48) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL3829415 | 0.81 | KDM4E (0.44) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL4640017 | 0.80 | KMT2A (0.49) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL12498237 | 0.80 | KDM4E (0.38) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3341752 | 0.80 | SIRT1 (0.42) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL3914130 | 0.80 | CD38 (0.44) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL3352032 | 0.80 | PARP1 (0.41) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29421066 | 0.80 | SIRT1 (0.39) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL7109139 | 0.80 | SIRT1 (0.39) | SIRT1BCAT2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817042-A2 | GLYCERIN BASED SYNTHESIS OF SILVER NANOPARTICLES AND NANOWIRES | Board of Regents, The University of Texas System (US) | 2007-08-15 | — | — | EP | claimed |
| WO-2007001453-A9 | GLYCERIN BASED SYNTHESIS OF SILVER NANOPARTICLES AND NANOWIRES | UNIV TEXAS (US) | 2007-03-01 | — | — | WO | claimed |
| WO-2007001453-A2 | GLYCERIN BASED SYNTHESIS OF SILVER NANOPARTICLES AND NANOWIRES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYTEM (US) | 2007-01-04 | — | — | WO | claimed |
| US-6458865-B2 | FOR DENTAL RESTORATION MATERIAL | CURATORS OF THE UNIVERSITY OF MISSOURI | 2002-10-01 | — | — | US | claimed |
| EP-1165627-A4 | PHOTOPOLYMERIZABLE VINYL ETHER BASED MONOMERIC FORMULATIONS AND POLYMERIZABLE COMPOSITIONS WHICH MAY INCLUDE CERTAIN NOVEL SPIROORTHOCARBONATES | UNIV MISSOURI (US) | 2002-03-20 | — | — | EP | claimed |
| EP-1165627-A1 | PHOTOPOLYMERIZABLE VINYL ETHER BASED MONOMERIC FORMULATIONS AND POLYMERIZABLE COMPOSITIONS WHICH MAY INCLUDE CERTAIN NOVEL SPIROORTHOCARBONATES | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000042080-A1 | PHOTOPOLYMERIZABLE VINYL ETHER BASED MONOMERIC FORMULATIONS AND POLYMERIZABLE COMPOSITIONS WHICH MAY INCLUDE CERTAIN NOVEL SPIROORTHOCARBONATES | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2000-07-20 | — | — | WO | claimed |
| CN-105722835-B | 3- aryl -5- substitution-isoquinoline-1-ketone compound and their therapy application | 癌症研究协会:皇家癌症医院 | 2018-07-31 | — | — | CN | disclosed |
| CN-104193750-B | Suppress mitotic Compounds and methods for by suppressing aurora kinase | 千禧药品公司 | 2018-04-27 | — | — | CN | disclosed |
| US-9688618-B2 | Hydroxamic acids and uses thereof | HAWAII BIOTECH, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20170036996-A1 | HYDROXAMIC ACIDS AND USES THEREOF | HAWAII BIOTECH, INC. | 2017-02-09 | — | — | US | disclosed |
| EP-2358779-A1 | FLUORINATED ETHER URETHANES AND METHODS OF USING THE SAME | 3M Innovative Properties Company (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2011089099-A1 | 4-PHENOXY-NICOTINAMIDE OR 4-PHENOXY-PYRIMIDINE-5-CARBOXAMIDE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-07-28 | — | — | WO | disclosed |
| WO-1999056913-A1 | COATED ABRASIVE ARTICLE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-11-11 | — | — | WO | disclosed |
| WO-1999057197-A1 | ENERGY CURED SEALANT COMPOSITION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-11-11 | — | — | WO | disclosed |
| WO-1998047047-A1 | TERNARY PHOTOINITIATOR SYSTEM FOR CURING OF EPOXY/POLYOL RESIN COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| EP-0789721-A2 | VISIBLE-LIGHT CURABLE EPOXY SYSTEM WITH ENHANCED DEPTH OF CURE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996013538-A2 | VISIBLE-LIGHT CURABLE EPOXY SYSTEM WITH ENHANCED DEPTH OF CURE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |
| US-4937381-A | Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitro-diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0027837-A1 | Substituted diphenyl ethers having utility as herbicides | ROHM AND HAAS COMPANY (US) | 1981-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170036996-A1 | HYDROXAMIC ACIDS AND USES THEREOF | HRH3, H1-3, H1-0 | SIRT1 2128/4885BCAT2 99/4885KDM4E 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.