Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.34 |
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22945628 | 0.82 | ACHE (0.41) | ACHEBCHEKMT2ATSHRMAPK1 | |
| SCHEMBL22946236 | 0.78 | BCHE (0.35) | ACHEBCHEKMT2ATSHRALDH1A1 | |
| SCHEMBL22946271 | 0.78 | ACHE (0.41) | ACHEBCHEKMT2ATSHRALDH1A1 | |
| SCHEMBL19726455 | 0.75 | ACHE (0.38) | ACHEBCHEKMT2ATSHRALDH1A1 | |
| SCHEMBL19726451 | 0.75 | CRHR1 (0.45) | ACHEBCHEKMT2ATSHRCRHR1 | |
| SCHEMBL19726449 | 0.75 | KMT2A (0.41) | ACHEBCHEKMT2ATSHRALDH1A1 | |
| SCHEMBL28709094 | 0.73 | RRM1 (0.44) | BCHEKMT2A | |
| SCHEMBL29633559 | 0.73 | RRM1 (0.44) | BCHEKMT2A | |
| SCHEMBL29633627 | 0.72 | TSHR (0.51) | KMT2ATSHRMAPK1HTTLMNA | |
| SCHEMBL22945604 | 0.72 | TSHR (0.51) | KMT2ATSHRMAPK1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021020429-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | 大正製薬株式会社 | 2021-02-04 | — | — | WO | disclosed |