Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22949646 | 0.95 | ALDH1A1 (0.41) | ALDH1A1MAPTTSHRPOLBCYP1A2 | |
| SCHEMBL22947430 | 0.92 | ALDH1A1 (0.43) | ALDH1A1MAPTTSHRPOLBCYP1A2 | |
| SCHEMBL22947426 | 0.90 | ADORA2A (0.38) | ALDH1A1MAPTTSHRPOLBKMT2A | |
| SCHEMBL22949087 | 0.89 | SMN1; SMN2 (0.38) | ALDH1A1MAPTTSHRPOLBCYP1A2 | |
| SCHEMBL22949531 | 0.87 | ADORA3 (0.36) | ALDH1A1MAPTTSHRPOLBKMT2A | |
| SCHEMBL22947384 | 0.85 | ADORA2A (0.40) | ALDH1A1MAPTTSHRPOLBKMT2A | |
| SCHEMBL22947375 | 0.84 | SMN1; SMN2 (0.40) | ALDH1A1MAPTTSHRPOLBCYP1A2 | |
| SCHEMBL22948448 | 0.83 | TSHR (0.37) | ALDH1A1MAPTTSHRPOLBKMT2A | |
| SCHEMBL22949661 | 0.83 | KDM4E (0.43) | ALDH1A1MAPTTSHRSMN1; SMN2KDM4E | |
| SCHEMBL22949634 | 0.82 | ADORA3 (0.38) | ALDH1A1MAPTTSHRPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210036245-A1 | HETEROAROMATIC COMPOUNDS | ETV6, FES, LEF1 | ALDH1A1 752/4885MAPT 3103/4885TSHR 3468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.