Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561646 | 0.84 | XDH (0.47) | XDHGABRA1GABRB2ALDH1A1CNR2 | |
| SCHEMBL29387575 | 0.82 | KDM1A (0.35) | KDM4ENPSR1PARP1CYP1A2AR | |
| SCHEMBL1426991 | 0.82 | KDM1A (0.35) | KDM4ENPSR1PARP1CYP1A2AR | |
| SCHEMBL12833024 | 0.81 | XDH (0.52) | XDHGABRA1GABRB2ALDH1A1CNR2 | |
| SCHEMBL30917473 | 0.81 | KDM1A (0.33) | PARP1KDM1AKCNH2KDM1B | |
| SCHEMBL8079708 | 0.77 | KDM1A (0.37) | ALDH1A1KDM4ENPSR1CYP1A2KDM1A | |
| SCHEMBL16922694 | 0.76 | KDM1A (0.39) | MAPTMEN1GAAKMT2AKDM4E | |
| SCHEMBL4576820 | 0.76 | XDH (0.68) | XDHGABRA1GABRB2ALDH1A1CNR2 | |
| SCHEMBL1738367 | 0.76 | ALDH1A1 (0.47) | XDHGABRA1GABRB2ALDH1A1CNR2 | |
| SCHEMBL2297312 | 0.76 | XDH (0.47) | XDHGABRA1GABRB2ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6025216-A | — | — | None | — | — | JP | disclosed |
| WO-2011103063-A1 | THERAPEUTIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-08-25 | — | — | WO | disclosed |
| US-7297378-B2 | Fluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-7297379-B2 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-20050258397-A1 | Fluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
| JP-H0625216-A | 1,3-DIOXANE DERIVATIVE, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME COMPOSITION | SEIKO EPSON CORP | 1994-02-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | SCO2, CHRM1, CBR1 | XDH 964/4885GABRA1 1198/4885GABRB2 1134/4885 |
| US-20050258397-A1 | Fluorinated fused aromatics and their use in liquid-crystal mixtures | AFF1, AFF2, AFF4 | XDH 68/4885GABRA1 2623/4885GABRB2 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.