Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084327 | 0.83 | KDM1A (0.35) | KDM1AKCNH2KDM1BKIF11CYP1A2 | |
| SCHEMBL3751790 | 0.82 | KDM4E (0.47) | CYP1A2CYP2D6CYP2C9CYP2C19NPSR1 | |
| SCHEMBL16922694 | 0.81 | KDM1A (0.39) | KDM1AKCNH2KDM1BKIF11CYP1A2 | |
| SCHEMBL12533678 | 0.79 | KDM1A (0.38) | KDM1AKCNH2KDM1BKIF11CYP1A2 | |
| SCHEMBL377446 | 0.79 | CYP1A2 (0.41) | KDM1AKCNH2KDM1BKIF11CYP1A2 | |
| SCHEMBL838854 | 0.78 | FAAH (0.37) | KDM4EFAAH | |
| SCHEMBL126440 | 0.78 | HTT (0.45) | KDM1AALDH1A1 | |
| SCHEMBL8070404 | 0.78 | IGF1R (0.35) | KDM1AKCNH2KDM1B | |
| SCHEMBL15352097 | 0.77 | KDM1A (0.37) | KDM1AKCNH2KDM1BKIF11CYP1A2 | |
| SCHEMBL855443 | 0.77 | LOXL2 (0.46) | KDM1AKCNH2KDM1BKIF11RCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101058549-A | 4-methoxy-1,3-phenyl disubstituted amide derivative | UNIV TIANJIN (CN) | 2007-10-24 | — | — | CN | claimed |
| CN-100594211-C | 4-methoxyl-1, 3-benzenedisubstituted amide derivs | UNIV TIANJIN | 2010-03-17 | — | — | CN | disclosed |
| CN-101641093-A | Imidazotriazines and imidazopyrimidines as kinase inhibitors | INCYTE CORP US | 2010-02-03 | — | — | CN | disclosed |
| CN-101058549-A | 4-methoxy-1,3-phenyl disubstituted amide derivative | UNIV TIANJIN (CN) | 2007-10-24 | — | — | CN | disclosed |
| EP-0655456-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5624918-A | Phosphonic diester derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0655456-A1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-05-31 | — | — | EP | disclosed |