Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930892 | 1.00 | ADORA2A (0.38) | ADORA2AADORA1TRPM8KCNA5KCNH2 | |
| Hydrochloric Acid SCHEMBL28719364 | 0.99 | SLC6A2 (0.38) | ADORA2AADORA1TRPM8KCNA5KCNH2 | |
| Hydrochloric Acid SCHEMBL28719366 | 0.99 | SLC6A2 (0.38) | ADORA2AADORA1TRPM8KCNA5KCNH2 | |
| SCHEMBL22952726 | 0.86 | ADORA2A (0.37) | ADORA2AADORA1TRPM8KCNA5KCNH2 | |
| Hydrochloric Acid SCHEMBL28715423 | 0.85 | SLC6A2 (0.36) | ADORA2AADORA1TRPM8KCNA5KCNH2 | |
| Hydrochloric Acid SCHEMBL28715421 | 0.85 | SLC6A2 (0.36) | ADORA2AADORA1TRPM8KCNA5KCNH2 | |
| SCHEMBL18704160 | 0.82 | CETP (0.43) | GPR139CETPSLC6A2 | |
| SCHEMBL171242 | 0.82 | GPR139 (0.43) | KCNA5KCNH2GPR139CTSSCTSK | |
| SCHEMBL734938 | 0.81 | KIF11 (0.43) | TRPM8CETPKIF11SLC6A2 | |
| SCHEMBL16563768 | 0.81 | PDE2A (0.40) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548849-B2 | Alcohol derivatives as KV7 potassium channel openers | H. LUNDBECK A/S (DK) | 2023-01-10 | — | — | US | disclosed |
| WO-2021023617-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. LUNDBECK A/S (DK) | 2021-02-11 | — | — | WO | disclosed |
| US-20210032196-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. LUNDBECK A/S (DK) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548849-B2 | Alcohol derivatives as KV7 potassium channel openers | KCNA7, KCNK17, KCNAB1 | ADORA2A 2087/4885ADORA1 1230/4885TRPM8 82/4885 |
| US-20210032196-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | KCNA7, KCNK17, KCNQ1 | ADORA2A 2026/4885ADORA1 1418/4885TRPM8 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.