Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24276602 | 0.89 | EP300 (0.42) | HDAC1DRD2DRD4DRD3EPHX2 | |
| SCHEMBL24276666 | 0.86 | DRD2 (0.41) | DRD2DRD4DRD3 | |
| SCHEMBL24276658 | 0.84 | EPHX2 (0.46) | HDAC1EPHX2EP300 | |
| SCHEMBL24276640 | 0.79 | L3MBTL1 (0.41) | HDAC1 | |
| SCHEMBL16330540 | 0.79 | MIF (0.43) | HDAC1EPHX2EP300 | |
| SCHEMBL24276638 | 0.78 | L3MBTL1 (0.42) | HDAC1EPHX2 | |
| SCHEMBL24276663 | 0.76 | DGAT1 (0.41) | — | |
| SCHEMBL24276664 | 0.76 | DGAT1 (0.41) | — | |
| SCHEMBL24276662 | 0.76 | DGAT1 (0.41) | — | |
| SCHEMBL12092247 | 0.76 | MIF (0.41) | KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021535-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2021-02-04 | — | — | WO | disclosed |