Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 8/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24276658 | 0.95 | EPHX2 (0.46) | EP300EPHX2FOLH1L3MBTL1HDAC1 | |
| SCHEMBL22953229 | 0.89 | POLB (0.37) | EP300EPHX2DRD2DRD4DRD3 | |
| SCHEMBL24276640 | 0.85 | L3MBTL1 (0.41) | L3MBTL1HDAC1 | |
| SCHEMBL24276666 | 0.85 | DRD2 (0.41) | DRD2DRD4DRD3FOLH1ABCB1 | |
| SCHEMBL24276638 | 0.84 | L3MBTL1 (0.42) | EPHX2L3MBTL1HDAC1 | |
| SCHEMBL24276653 | 0.84 | DGAT1 (0.45) | EP300GLA | |
| SCHEMBL24276655 | 0.84 | DGAT1 (0.45) | EP300GLA | |
| SCHEMBL24276654 | 0.84 | DGAT1 (0.45) | EP300GLA | |
| SCHEMBL16330540 | 0.83 | MIF (0.43) | EP300EPHX2L3MBTL1HDAC1 | |
| SCHEMBL11887044 | 0.81 | FOLH1 (0.40) | EP300EPHX2FOLH1GLAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022055877-A2 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-03-17 | — | — | WO | disclosed |