Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22954960 | 0.93 | GRM4 (0.39) | GRM4SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL22955122 | 0.91 | CHRNB2 (0.34) | GRM4SMN1; SMN2POLBMAPTNPC1 | |
| SCHEMBL22955948 | 0.89 | GAA (0.44) | SMN1; SMN2POLBEPHX2GAAGPR119 | |
| SCHEMBL22942059 | 0.85 | RAB9A (0.35) | GRM4SMN1; SMN2POLBMAPTNPC1 | |
| SCHEMBL24120293 | 0.83 | RAB9A (0.38) | GRM4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL22955543 | 0.82 | RAB9A (0.41) | GRM4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL22955944 | 0.82 | DRD2 (0.40) | GRM4EPHX2GAAKDR | |
| SCHEMBL22955565 | 0.81 | CHRNB2 (0.47) | SMN1; SMN2EPHX2GAA | |
| SCHEMBL22992066 | 0.80 | GRM4 (0.39) | GRM4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL22954994 | 0.80 | PDE2A (0.45) | SMN1; SMN2EPHX2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018833-A1 | CYCLOHEXANEDIONES AS HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-02-04 | — | — | WO | disclosed |