Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22956060 | 0.82 | GUSB (0.53) | GUSBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL29824605 | 0.80 | NPC1 (0.49) | GUSBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL2951537 | 0.80 | NPC1 (0.49) | GUSBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL22955333 | 0.80 | AMY1A (0.57) | GUSBNPC1RAB9AAMY1AFGFR1 | |
| SCHEMBL22955871 | 0.76 | HPGD (0.72) | GUSBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11528753 | 0.75 | NPC1 (0.67) | ALDH1A1HPGDKDM4EHSD17B10MAPK1 | |
| SCHEMBL13405888 | 0.75 | ALDH1A1 (0.71) | GUSBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL7547916 | 0.74 | ACHE (0.42) | ALDH1A1HPGDKDM4EHSD17B10MAPK1 | |
| SCHEMBL1171146 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EHSD17B10MAPK1 | |
| SCHEMBL346502 | 0.73 | GUSB (0.60) | GUSBALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022061-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |