Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22957683 | 0.86 | SLC6A4 (0.54) | NPY1RNPY2RPDE4AKCNH2NTRK1 | |
| SCHEMBL24180134 | 0.83 | PDE4A (0.47) | LMNANPY1RNPY2RPDE4APDE4B | |
| SCHEMBL22957692 | 0.82 | LMNA (0.54) | LMNANPY1RNPY2RMEN1KMT2A | |
| SCHEMBL22957846 | 0.82 | NPY1R (0.70) | LMNANPY1RNPY2RPDE4AKCNH2 | |
| SCHEMBL24180131 | 0.81 | PDE4A (0.44) | NPY1RNPY2RPDE4APDE4BPDE4C | |
| SCHEMBL14012652 | 0.81 | KCNH2 (0.52) | LMNAKCNH2NTRK1TACR1KDM1A | |
| SCHEMBL22957878 | 0.79 | NPY1R (0.56) | LMNANPY1RNPY2RPDE4AKCNH2 | |
| SCHEMBL20472386 | 0.78 | CSNK2A1 (0.51) | NPY1RNPY2RPDE4ASLC6A4 | |
| SCHEMBL29786553 | 0.78 | CSNK2A1 (0.51) | NPY1RNPY2RPDE4ASLC6A4 | |
| SCHEMBL18783703 | 0.78 | NPY1R (0.41) | LMNANPY1RNPY2RPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | RIPK1, RIPK3, RIPK4 | LMNA 3449/4885NPY1R 2919/4885NPY2R 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.