Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.70 |
| ▸ | NPY2R | P49146 | 1/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22957878 | 0.88 | NPY1R (0.56) | NPY1RNPY2REPHX2MEN1KMT2A | |
| SCHEMBL22957683 | 0.85 | SLC6A4 (0.54) | NPY1RNPY2RPDE4ARECQLKCNH2 | |
| SCHEMBL22957807 | 0.83 | NPY1R (0.65) | NPY1RNPY2REPHX2MEN1KMT2A | |
| SCHEMBL22957853 | 0.83 | NPY1R (0.49) | NPY1RNPY2RMEN1KMT2APKM | |
| SCHEMBL22957684 | 0.82 | LMNA (0.56) | NPY1RNPY2REPHX2MEN1KMT2A | |
| SCHEMBL22389479 | 0.82 | NPY1R (0.47) | NPY1RNPY2REPHX2PDE4ARECQL | |
| SCHEMBL24180131 | 0.80 | PDE4A (0.44) | NPY1RNPY2RPDE4APDE4BPDE4C | |
| SCHEMBL22957686 | 0.78 | NPY1R (0.53) | NPY1RNPY2RMEN1KMT2APDE4A | |
| SCHEMBL20472386 | 0.77 | CSNK2A1 (0.51) | NPY1RNPY2RPDE4A | |
| SCHEMBL29786553 | 0.77 | CSNK2A1 (0.51) | NPY1RNPY2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913738-B2 | Aminotriazolopyridines as kinase inhibitors | RIPK1, RIPK3, RIPK4 | NPY1R 2919/4885NPY2R 3582/4885EPHX2 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.