Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.34 |
| ▸ | ESR1 | P03372 | 10/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22958577 | 0.97 | PBRM1 (0.38) | PBRM1CASP1CASP7HSD17B10ESR2 | |
| SCHEMBL22958590 | 0.91 | PBRM1 (0.36) | PBRM1CASP1CASP7HSD17B10ESR2 | |
| SCHEMBL22958589 | 0.83 | PBRM1 (0.31) | PBRM1ESR2ESR1BRD4HSD17B1 | |
| SCHEMBL22958555 | 0.82 | ESPL1 (0.40) | CASP1CASP7HSD17B10ESR2ESR1 | |
| SCHEMBL22958591 | 0.80 | MAOA (0.41) | ESR2ESR1MEN1MAPK1KMT2A | |
| SCHEMBL30166132 | 0.77 | CASP1 (0.38) | PBRM1CASP1CASP7HSD17B10ESR2 | |
| SCHEMBL22958595 | 0.74 | CYP2C19 (0.39) | — | |
| SCHEMBL22958579 | 0.70 | CYP2C19 (0.41) | MAPK1 | |
| SCHEMBL22958597 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL7624438 | 0.67 | PBRM1 (0.44) | PBRM1CASP1CASP7HSD17B10BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023144-A1 | FLUORENOXIME ESTER COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 常州强力电子新材料股份有限公司 | 2021-02-11 | — | — | WO | disclosed |