Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.73 |
| ▸ | THRB | P10828 | 6/20 | 0.73 |
| ▸ | PNLIP | P16233 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584863 | 0.88 | THRB (0.57) | RORCTHRBRAB9ATHRALMNA | |
| SCHEMBL22959340 | 0.87 | RORC (0.67) | RORCTHRBTHRA | |
| SCHEMBL22959176 | 0.85 | RORC (0.70) | RORCTHRBTHRA | |
| SCHEMBL22959162 | 0.85 | RORC (0.70) | RORCTHRBTHRA | |
| SCHEMBL8799780 | 0.84 | RORC (0.68) | RORCTHRBTHRA | |
| SCHEMBL22959104 | 0.83 | RORC (0.67) | RORCTHRBTHRALMNA | |
| SCHEMBL22959250 | 0.82 | RORC (0.72) | RORCTHRBTHRA | |
| SCHEMBL5619231 | 0.82 | THRB (0.73) | RORCTHRBTHRA | |
| SCHEMBL22959193 | 0.82 | RORC (0.74) | RORCTHRBTHRA | |
| SCHEMBL8902087 | 0.81 | THRB (0.65) | RORCTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026179-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-11 | — | — | WO | disclosed |