Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MDM4 | O15151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745317 | 0.80 | KMT2A (0.49) | KMT2AMDM4TP53FABP5FABP7 | |
| SCHEMBL7134570 | 0.77 | KMT2A (0.52) | KMT2AMDM4TP53FABP5FABP7 | |
| SCHEMBL28773360 | 0.77 | KMT2A (0.49) | KMT2AMDM4TP53FABP5FABP7 | |
| SCHEMBL1965001 | 0.77 | KMT2A (0.44) | KMT2AMDM4TP53FABP5FABP7 | |
| SCHEMBL119587 | 0.76 | MDM4 (0.56) | MDM4TP53MDM2ALDH1A1CASP3 | |
| SCHEMBL16397974 | 0.76 | KMT2A (0.41) | KMT2AMDM4TP53MDM2FABP5 | |
| SCHEMBL29398165 | 0.76 | MDM4 (0.56) | MDM4TP53MDM2ALDH1A1CASP3 | |
| SCHEMBL2309871 | 0.76 | MDM4 (0.56) | MDM4TP53MDM2ALDH1A1CASP3 | |
| SCHEMBL119362 | 0.76 | MDM4 (0.56) | MDM4TP53MDM2ALDH1A1CASP3 | |
| SCHEMBL29497566 | 0.76 | MDM4 (0.56) | MDM4TP53MDM2ALDH1A1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3455234-B1 | SECO MACROLIDE COMPOUNDS | SELVITA D O O (HR) | 2026-04-01 | — | — | EP | disclosed |
| US-11512096-B2 | Seco macrolide compounds | SELVITA D.O.O. (HR) | 2022-11-29 | — | — | US | disclosed |
| US-20210198278-A1 | SECO MACROLIDE COMPOUNDS | SELVITA D.O.O. (HR) | 2021-07-01 | — | — | US | disclosed |
| US-10919910-B2 | Seco macrolide compounds | FIDELTA D.O.O. (HR) | 2021-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198278-A1 | SECO MACROLIDE COMPOUNDS | SEC61B, SEC16A, SEC61A1 | KMT2A 4255/4885MDM4 3271/4885TP53 4852/4885 |
| US-11512096-B2 | Seco macrolide compounds | SEC61B, SEC16A, SEC61A1 | KMT2A 4255/4885MDM4 3271/4885TP53 4852/4885 |
| US-10919910-B2 | Seco macrolide compounds | SEC61B, SEC16A, SEC61A1 | KMT2A 4255/4885MDM4 3271/4885TP53 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.