SCHEMBL22960729

SCHEMBL22960729

C=CCC(CC=O)NC(=O)OC(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 9/20 0.48
▸ MAPT P10636 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA7 P43166 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ CYP2D6 P10635 1/20 0.38
▸ CTSS P25774 2/20 0.36
▸ AAK1 Q2M2I8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7743860 0.93 CTSK (0.49) CTSKMAPTCA1CA2CA7
SCHEMBL31127632 0.92 CTSK (0.54) CTSKCA1CA2CA7ATM
SCHEMBL3378594 0.86 CTSK (0.44) CTSKMAPTCA1CA2CA7
SCHEMBL5196572 0.85 CTSK (0.45) CTSKMAPTCA1CA2CA7
SCHEMBL12290180 0.85 CTSK (0.45) CTSKMAPTCA1CA2CA7
SCHEMBL211054 0.85 CTSK (0.45) CTSKMAPTCA1CA2CA7
SCHEMBL211053 0.85 CTSK (0.45) CTSKMAPTCA1CA2CA7
SCHEMBL11137176 0.84 CTSK (0.44) CTSKMAPTCA1CA2CA7
SCHEMBL1722623 0.83 CTSK (0.50) CTSKCA1CA2CA7ATM
SCHEMBL29955586 0.83 CTSK (0.50) CTSKCA1CA2CA7ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3455234-B1 SECO MACROLIDE COMPOUNDS SELVITA D O O (HR) 2026-04-01 — — EP disclosed
US-11512096-B2 Seco macrolide compounds SELVITA D.O.O. (HR) 2022-11-29 — — US disclosed
US-20210198278-A1 SECO MACROLIDE COMPOUNDS SELVITA D.O.O. (HR) 2021-07-01 — — US disclosed
US-10919910-B2 Seco macrolide compounds FIDELTA D.O.O. (HR) 2021-02-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198278-A1 SECO MACROLIDE COMPOUNDS SEC61B, SEC16A, SEC61A1 CTSK 1034/4885MAPT 3885/4885CA1 4884/4885
US-11512096-B2 Seco macrolide compounds SEC61B, SEC16A, SEC61A1 CTSK 1034/4885MAPT 3885/4885CA1 4884/4885
US-10919910-B2 Seco macrolide compounds SEC61B, SEC16A, SEC61A1 CTSK 1034/4885MAPT 3885/4885CA1 4884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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