Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447912 | 0.81 | ENPP2 (0.52) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31243807 | 0.81 | ENPP2 (0.52) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16065807 | 0.75 | LTA4H (0.39) | CA1CA2 | |
| SCHEMBL29953751 | 0.75 | ENPP2 (0.46) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29952210 | 0.73 | AHR (0.51) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1979081 | 0.73 | FGFR1 (0.41) | ENPP2MAOB | |
| SCHEMBL23364624 | 0.73 | ENPP2 (0.31) | ENPP2 | |
| SCHEMBL8830 | 0.72 | ENPP2 (0.61) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31437777 | 0.71 | ENPP2 (0.48) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23364822 | 0.69 | PDK2 (0.34) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040079-A1 | 10H-phenothiazine ferroptosis inhibitor as well as the preparative method and the use thereof | Chengdu Henghao Investment Co. Limited (CN) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040079-A1 | 10H-phenothiazine ferroptosis inhibitor as well as the preparative method and the use thereof | AIFM2, FECH, GPX4 | ENPP2 3907/4885TUBB4A 2696/4885TUBB 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.