Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987184 | 0.79 | IMPDH2 (0.44) | IMPDH2IMPDH1PIN1MAPK10PKN1 | |
| SCHEMBL4387879 | 0.77 | IMPDH2 (0.46) | IMPDH2IMPDH1PIN1MAPK10PKN1 | |
| SCHEMBL1245512 | 0.76 | RHEB (0.49) | IMPDH2IMPDH1PIN1MAPK10PKN1 | |
| SCHEMBL1794997 | 0.76 | CSNK1D (0.47) | IMPDH2IMPDH1PIN1MAPK10PKN1 | |
| SCHEMBL11249156 | 0.76 | MASP2 (0.48) | IMPDH2IMPDH1PIN1MAPK10PKN1 | |
| SCHEMBL27306100 | 0.76 | IMPDH2 (0.44) | IMPDH2IMPDH1PIN1MAPK10PKN1 | |
| SCHEMBL2712161 | 0.76 | PIN1 (0.46) | IMPDH2IMPDH1PIN1MAPK10PKN1 | |
| SCHEMBL13677328 | 0.75 | CSNK1D (0.46) | IMPDH2IMPDH1PIN1MAPK10CSNK1A1 | |
| SCHEMBL9063730 | 0.75 | GRIN1 (0.51) | IMPDH2IMPDH1PIN1MAPK10PKN1 | |
| SCHEMBL23676436 | 0.73 | TXN (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040087-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040087-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | IMPDH2 3909/4885IMPDH1 3785/4885PIN1 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.