Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16421862 | 0.85 | GAA (0.59) | PTGDR2GAAHSD17B10KDM4ETNF | |
| SCHEMBL22965154 | 0.82 | KDM4E (0.62) | PTGDR2GAAHSD17B10KDM4ETNF | |
| SCHEMBL22965212 | 0.81 | PTGDR2 (0.59) | PTGDR2GAAHSD17B10KDM4ETNF | |
| SCHEMBL22965246 | 0.81 | PTGDR2 (0.54) | PTGDR2GAAL3MBTL1HSD17B10KDM4E | |
| SCHEMBL22965222 | 0.80 | ALDH1A1 (0.54) | PTGDR2HSD17B10KDM4ETNFHTT | |
| SCHEMBL22965231 | 0.80 | TSHR (0.59) | PTGDR2L3MBTL1HSD17B10KDM4ETNF | |
| SCHEMBL25400141 | 0.78 | KDM4E (0.53) | PTGDR2GAAHSD17B10KDM4ETNF | |
| SCHEMBL30536652 | 0.78 | KDM4E (0.53) | PTGDR2GAAHSD17B10KDM4ETNF | |
| SCHEMBL11201897 | 0.78 | HTT (0.55) | L3MBTL1KDM4EHTTLMNASMN1; SMN2 | |
| SCHEMBL7745965 | 0.78 | SMN1; SMN2 (0.58) | PTGDR2HSD17B10KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |