Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 7/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965243 | 0.81 | SLC9A1 (0.61) | TNFKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL22965223 | 0.79 | TNF (0.49) | TNFCTNNB1GAACREBBPCNR1 | |
| SCHEMBL22965161 | 0.78 | TNF (0.45) | TNFCTNNB1GAAKDM4EHSD17B10 | |
| SCHEMBL13825807 | 0.78 | SLC9A1 (0.62) | KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL16526235 | 0.77 | SLC9A1 (0.60) | ASAH1ALDH1A1HTTLMNA | |
| SCHEMBL12393295 | 0.77 | SLC9A1 (0.63) | KDM4EHSD17B10LMNA | |
| SCHEMBL22965158 | 0.76 | KDM4E (0.44) | TNFKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29328629 | 0.74 | GAA (0.46) | TNFGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL15141852 | 0.73 | EGLN3 (0.65) | GAAKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL2216669 | 0.72 | SIRT2 (0.48) | ASAH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |