Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965217 | 0.82 | KMO (0.51) | KDM4EHSD17B10TBXAS1 | |
| SCHEMBL22965272 | 0.81 | KMO (0.58) | TNFKDM4EPTGDR2GAACTNNB1 | |
| SCHEMBL26067897 | 0.79 | SLC9A1 (0.51) | KDM4EGAAALDH1A1HTTLMNA | |
| SCHEMBL22965233 | 0.78 | TNF (0.45) | TNFKDM4EGAACTNNB1ALDH1A1 | |
| SCHEMBL22965255 | 0.77 | KDM4E (0.44) | TNFKDM4EGAACTNNB1HSD17B10 | |
| SCHEMBL22965243 | 0.76 | SLC9A1 (0.61) | TNFKDM4EPTGDR2ALDH1A1HSD17B10 | |
| SCHEMBL30035836 | 0.75 | SLC9A1 (0.49) | KDM4EHSD17B10HPGDHTTLMNA | |
| SCHEMBL23161358 | 0.75 | KMO (0.35) | — | |
| SCHEMBL1398456 | 0.74 | MAPT (0.46) | TNFKDM4ECTNNB1HSD17B10CREBBP | |
| SCHEMBL1398484 | 0.74 | CNR1 (0.47) | TNFKDM4EGAACTNNB1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234609-B1 | METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS | POLYPLUS TRANSFECTION (FR) | 2024-07-17 | — | — | EP | disclosed |
| EP-4234609-A1 | METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS | PolyPlus Transfection (FR) | 2023-08-30 | — | — | EP | disclosed |
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |