Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213739 | 0.96 | SIRT2 (0.47) | SIRT2SIRT1SIRT3ASAH1MGLL | |
| SCHEMBL4952678 | 0.77 | SIRT2 (0.56) | SIRT2SIRT1SIRT3HDAC3HDAC4 | |
| SCHEMBL2217546 | 0.77 | FAAH (0.43) | SIRT2MGLLHPSEBRD4POLB | |
| SCHEMBL11752297 | 0.74 | SIRT2 (0.56) | SIRT2SIRT1SIRT3HDAC3HDAC4 | |
| SCHEMBL2216539 | 0.73 | SIRT2 (0.55) | SIRT2SIRT1SIRT3HDAC3HDAC4 | |
| SCHEMBL24437290 | 0.73 | SIRT2 (0.41) | SIRT2SIRT1SIRT3ASAH1MGLL | |
| SCHEMBL22970124 | 0.73 | BACE1 (0.44) | SIRT2SIRT1SIRT3ASAH1MGLL | |
| SCHEMBL2217398 | 0.72 | HPSE (0.45) | SIRT2MGLLHPSEBRD4POLB | |
| SCHEMBL12435616 | 0.72 | HPSE (0.45) | SIRT2MGLLHPSEBRD4POLB | |
| SCHEMBL22965233 | 0.72 | TNF (0.45) | ASAH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | ETH ZURICH (CH) | 2011-07-21 | — | — | US | claimed |
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | ETH ZURICH (CH) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | MTCL3, BICRA, HMGB3 | SIRT2 1266/4885SIRT1 1110/4885SIRT3 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.