SCHEMBL22965243

SCHEMBL22965243

CCOC(=O)CCCn1nnc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 7/20 0.61
EGLN3 Q9H6Z9 1/20 0.58
MAPK1 P28482 1/20 0.54
KDM4E B2RXH2 1/20 0.53
MAPT P10636 1/20 0.53
LMNA P02545 3/20 0.53
KMT2A Q03164 2/20 0.53
RAB9A P51151 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
MEN1 O00255 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
USP2 O75604 1/20 0.52
TP53 P04637 1/20 0.52
HSD17B10 Q99714 1/20 0.52
NPC1 O15118 1/20 0.51
ALDH1A1 P00352 1/20 0.50
TNF P01375 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13825807 0.96 SLC9A1 (0.62) SLC9A1EGLN3MAPK1KDM4EMAPT
SCHEMBL12393295 0.95 SLC9A1 (0.63) SLC9A1EGLN3MAPK1KDM4EMAPT
SCHEMBL15141852 0.92 EGLN3 (0.65) SLC9A1EGLN3MAPK1KDM4EMAPT
SCHEMBL22965158 0.84 KDM4E (0.44) SLC9A1EGLN3MAPK1KDM4EHSD17B10
SCHEMBL1842634 0.84 SMN1; SMN2 (0.61) KDM4ELMNAKMT2ARAB9ASMN1; SMN2
SCHEMBL2490943 0.83 TP53 (0.67) SLC9A1KDM4ELMNAKMT2ARAB9A
SCHEMBL23880032 0.82 SLC9A1 (0.62) SLC9A1EGLN3MAPK1KDM4EMAPT
SCHEMBL22965247 0.82 HCAR3 (0.49) KDM4EMAPTLMNAKMT2ARAB9A
SCHEMBL18388038 0.81 RAB9A (0.44) SLC9A1EGLN3MAPK1MAPTLMNA
SCHEMBL22965233 0.81 TNF (0.45) KDM4ELMNAHSD17B10ALDH1A1TNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4234609-B1 METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS POLYPLUS TRANSFECTION (FR) 2024-07-17 EP disclosed
EP-4234609-A1 METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS PolyPlus Transfection (FR) 2023-08-30 EP disclosed
WO-2021023796-A1 COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS POLYPLUS TRANSFECTION (FR) 2021-02-11 WO disclosed