Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.41 |
| ▸ | TNF | P01375 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965272 | 0.85 | KMO (0.58) | KDM4EKMOHSD17B10TNFGAA | |
| SCHEMBL29328557 | 0.81 | KMO (0.63) | KDM4EKMOHSD17B10TBXAS1PDE4B | |
| SCHEMBL8803921 | 0.77 | SLC9A1 (0.40) | KMO | |
| SCHEMBL22965161 | 0.77 | TNF (0.45) | KDM4EHSD17B10TBXAS1TNFGAA | |
| SCHEMBL22965158 | 0.77 | KDM4E (0.44) | KDM4EHSD17B10TBXAS1TNF | |
| SCHEMBL13332357 | 0.76 | KDM4E (0.44) | KDM4EKMOHSD17B10TNFGAA | |
| SCHEMBL21471470 | 0.76 | KMO (0.59) | KDM4EKMOHSD17B10TBXAS1TNF | |
| SCHEMBL1980738 | 0.76 | TNF (0.43) | KDM4EKMOHSD17B10TNFPDE4B | |
| SCHEMBL7836228 | 0.76 | TNF (0.51) | TBXAS1TNF | |
| SCHEMBL1398471 | 0.75 | CACNA1H (0.44) | KDM4EKMOHSD17B10TNFGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234609-B1 | METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS | POLYPLUS TRANSFECTION (FR) | 2024-07-17 | — | — | EP | disclosed |
| EP-4234609-A1 | METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS | PolyPlus Transfection (FR) | 2023-08-30 | — | — | EP | disclosed |
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |