SCHEMBL2296554

SCHEMBL2296554

O=C(O)c1c(-c2ccc(Cl)cc2)cc2ccccc2c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 8/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C8 P10632 1/20 0.54
CYP2C9 P11712 1/20 0.54
GPR84 Q9NQS5 1/20 0.52
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
MEN1 O00255 2/20 0.49
HPGD P15428 2/20 0.49
KMT2A Q03164 2/20 0.49
CYP1A2 P05177 1/20 0.49
GLA P06280 1/20 0.49
CYP2C19 P33261 1/20 0.49
HSD17B10 Q99714 1/20 0.49
ANO1 Q5XXA6 1/20 0.46
MAPT P10636 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CTRC Q99895 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27608 0.89 MEN1 (0.56) DHODHCYP3A4CYP2C8CYP2C9GPR84
SCHEMBL2354661 0.85 GPR84 (0.52) DHODHGPR84KDM4EALDH1A1MEN1
SCHEMBL2354413 0.81 KMT2A (0.50) DHODHCYP3A4CYP2C8CYP2C9KDM4E
SCHEMBL28589092 0.77 MEN1 (0.53) CYP2C9GPR84KDM4EALDH1A1MEN1
SCHEMBL338938 0.76 MEN1 (0.61) DHODHCYP3A4CYP2C8CYP2C9GPR84
SCHEMBL21879684 0.76 MEN1 (0.66) DHODHGPR84KDM4EALDH1A1MEN1
SCHEMBL2354608 0.75 DHODH (0.49) DHODHCYP3A4CYP2C8CYP2C9KDM4E
SCHEMBL2357290 0.75 LDHA (0.51) CYP3A4CYP2C9KDM4EALDH1A1MEN1
SCHEMBL1514435 0.74 MEN1 (0.58) GPR84KDM4EALDH1A1MEN1HPGD
SCHEMBL245378 0.74 CYP1A2 (0.62) DHODHCYP3A4KDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8354359-B2 Heat-sensitive adhesive agent and heat-sensitive adhesive sheet RICOH COMPANY, LTD. (JP) 2013-01-15 US disclosed
EP-2062953-B1 Heat-sensitive adhesive material RICOH CO LTD (JP) 2011-08-17 EP disclosed
US-7993732-B2 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2011-08-09 US disclosed
EP-2062953-A1 Heat-sensitive adhesive material Ricoh Company, Ltd. (JP) 2009-05-27 EP disclosed
US-20090130441-A1 HEAT-SENSITIVE ADHESIVE MATERIAL RICOH COMPANY, LTD (JP) 2009-05-21 US disclosed
US-20080176012-A1 Heat-sensitive adhesive agent and heat-sensitive adhesive sheet RICOH COMPANY, LTD. (JP) 2008-07-24 US disclosed
EP-1897925-A1 Heat-sensitive adhesive agent and heat-sensitive adhesive sheet Ricoh Company, Ltd. (JP) 2008-03-12 EP disclosed
US-20080026205-A1 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2008-01-31 US disclosed
EP-1882726-A1 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material Ricoh Company, Ltd. (JP) 2008-01-30 EP disclosed