SCHEMBL338938

SCHEMBL338938

O=C(O)c1c(O)c(-c2ccccc2)cc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
KDM4E B2RXH2 3/20 0.61
ALDH1A1 P00352 2/20 0.61
HPGD P15428 2/20 0.61
CYP1A2 P05177 2/20 0.61
GLA P06280 1/20 0.61
CYP2C19 P33261 1/20 0.61
HSD17B10 Q99714 1/20 0.61
DHODH Q02127 5/20 0.53
PDE10A Q9Y233 1/20 0.53
MAPT P10636 1/20 0.51
MPI P34949 1/20 0.51
ME2 P23368 1/20 0.51
ME1 P48163 1/20 0.51
ME3 Q16798 1/20 0.51
PTPN1 P18031 2/20 0.49
CYP3A4 P08684 2/20 0.47
CYP2C8 P10632 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8902889 0.87 CYP1A2 (0.54) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL5553181 0.87 MEN1 (0.49) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL27608 0.86 MEN1 (0.56) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL21879684 0.86 MEN1 (0.66) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL12476186 0.81 MEN1 (0.59) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL1514435 0.81 MEN1 (0.58) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL29779946 0.80 CYP1A2 (0.68) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL88986 0.80 CYP1A2 (0.68) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL25424740 0.80 MEN1 (0.60) MEN1KMT2AKDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL11313207 0.79 CYP1A2 (0.66) MEN1KMT2AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0100196-B1 THERMALLY RESPONSIVE RECORD MATERIAL APPLETON PAPERS INC. (US) 1986-07-30 EP claimed
US-4470057-A CHROMOGENIC COMPOUND, ACIDIC DEVELOPERS, AND PHENYLHYDROXYNAPHTHOATE APPLETON PAPERS INC. (US) 1984-09-04 US claimed
EP-3719617-B1 MULTIFUNCTIONAL PEN MITSUBISHI PENCIL CO (JP) 2023-08-16 EP disclosed
US-11221686-B2 Multifunction pen MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2022-01-11 US disclosed
US-20200363881-A1 MULTIFUNCTION PEN MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2020-11-19 US disclosed
EP-3719617-A1 MULTIFUNCTIONAL PEN Mitsubishi Pencil Company, Limited (JP) 2020-10-07 EP disclosed
WO-2016198784-A1 THERMOCHROMIC MAKEUP OR TATTOOING MICROCAPSULES AND COMPOSITION INK AND OUT SAS (FR) 2016-12-15 WO disclosed
US-8616797-B2 Thermosensitive decolorable ink composition MITSUBISHI PENCIL COMPANY, LTD. (JP) 2013-12-31 US disclosed
EP-2412762-A1 THERMOSENSITIVE DECOLORABLE INK COMPOSITION Mitsubishi Pencil Company, Limited (JP) 2012-02-01 EP disclosed
US-20120014740-A1 THERMOSENSITIVE DECOLORABLE INK COMPOSITION MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-20090312313-A1 COMPOUND HAVING TGFBETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME KIRIN BEER KABUSHIKI KAISHA (JP) 2009-12-17 US disclosed
EP-0165041-B1 RECORD MATERIAL APPLETON PAPERS INC. (US) 1989-01-04 EP disclosed
US-4702983-A Electrophotographic photoreceptor comprising bis-azo pigment MITSUBISHI PAPER MILLS, LTD. (JP) 1987-10-27 US disclosed
EP-0234247-A2 Electrophotographic photoreceptor and electrophotographic process MITSUBISHI PAPER MILLS, LTD. (JP) 1987-09-02 EP disclosed
US-4675707-A IMPROVED BACKGROUND USING A PHENYL-BIS P-HYDROXYPHENYL ALKANE DEVELOPER; FACSIMILE COPIERS APPLETON PAPERS INC. (US) 1987-06-23 US disclosed
US-4586061-A CONTAINING CHROMOGENIC MATERIAL AND A BISPHENOL DEVELOPER APPLETON PAPERS INC. (US) 1986-04-29 US disclosed
EP-0165041-A2 Record material APPLETON PAPERS INC. (US) 1985-12-18 EP disclosed
US-4520379-A CHROMOGEN, ACIDIC DEVELOPER AND BINDER ON SUPPORT APPLETON PAPERS INC. (US) 1985-05-28 US disclosed
US-4470057-A CHROMOGENIC COMPOUND, ACIDIC DEVELOPERS, AND PHENYLHYDROXYNAPHTHOATE APPLETON PAPERS INC. (US) 1984-09-04 US disclosed
US-4470057-A CHROMOGENIC COMPOUND, ACIDIC DEVELOPERS, AND PHENYLHYDROXYNAPHTHOATE APPLETON PAPERS INC. (US) 1984-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312313-A1 COMPOUND HAVING TGFBETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME TGFB1, TGFBR1, TGFBR2 MEN1 1711/4885KMT2A 2535/4885KDM4E 1066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.