Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25745260 | 1.00 | FAAH (0.33) | FAAHJAK3BTKAAK1CA1 | |
| SCHEMBL8647813 | 1.00 | FAAH (0.33) | FAAHJAK3BTKAAK1CA1 | |
| SCHEMBL30414771 | 0.90 | FAAH (0.31) | FAAHJAK3BTK | |
| SCHEMBL30414719 | 0.90 | FAAH (0.31) | FAAHJAK3BTK | |
| SCHEMBL30414734 | 0.90 | FAAH (0.31) | FAAHJAK3BTK | |
| SCHEMBL12201977 | 0.83 | FAAH (0.32) | FAAHJAK3BTKAAK1 | |
| SCHEMBL20061314 | 0.83 | CA1 (0.33) | FAAHJAK3BTKCA1CA2 | |
| SCHEMBL60274 | 0.83 | FAAH (0.32) | FAAHJAK3BTKAAK1 | |
| SCHEMBL18796420 | 0.79 | CA14 (0.41) | AAK1CA1CA2CA7DGAT1 | |
| SCHEMBL7021061 | 0.79 | CA14 (0.41) | AAK1CA1CA2CA7DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590096-B2 | Imidazo[2,1-f][1,2,4]triazin-4-amine as TLR8 agonists | BeOne Medicines | GmbH (CH) | 2026-03-31 | — | — | US | disclosed |
| US-20240294488-A1 | ISOTOPOLOGES, SALTS, CRYSTALLINE FORMS, STEREOISOMERS, OF METHYLONE AND ETHYLONE AND METHODS OF USE THEREOF | TERRAN BIOSCIENCES INC (US) | 2024-09-05 | — | — | US | disclosed |
| US-20230192642-A1 | ISOTOPOLOGUES SALTS, CRYSTALLINE FORMS, STEREOISOMERS, OF METHYLONE AND ETHYLONE AND METHODS OF USE THEREOF | TERRAN BIOSCIENCES INC. | 2023-06-22 | — | — | US | disclosed |
| US-20230192642-A1 | ISOTOPOLOGUES SALTS, CRYSTALLINE FORMS, STEREOISOMERS, OF METHYLONE AND ETHYLONE AND METHODS OF USE THEREOF | TERRAN BIOSCIENCES INC. | 2023-06-22 | — | — | US | disclosed |
| US-20220289752-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES USED AS TLR8 AGONISTS | BEONE MEDICINES I GMBH (CH) | 2022-09-15 | — | — | US | disclosed |
| EP-4008720-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVE USED AS TLR8 AGONIST | BeiGene, Ltd. (KY) | 2022-06-08 | — | — | EP | disclosed |
| EP-4008720-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVE USED AS TLR8 AGONIST | BeiGene, Ltd. (KY) | 2022-06-08 | — | — | EP | disclosed |
| CN-114206872-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR8 agonists | 百济神州有限公司 | 2022-03-18 | — | — | CN | disclosed |
| WO-2021023105-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVE USED AS TLR8 AGONIST | 百济神州有限公司 | 2021-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192642-A1 | ISOTOPOLOGUES SALTS, CRYSTALLINE FORMS, STEREOISOMERS, OF METHYLONE AND ETHYLONE AND METHODS OF USE THEREOF | PYGB, NR3C2, CYP11B1 | FAAH 2070/4885JAK3 2225/4885BTK 4741/4885 |
| US-20220289752-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES USED AS TLR8 AGONISTS | TLR8, TLR1, TLR7 | FAAH 2437/4885JAK3 224/4885BTK 853/4885 |
| US-20240294488-A1 | ISOTOPOLOGES, SALTS, CRYSTALLINE FORMS, STEREOISOMERS, OF METHYLONE AND ETHYLONE AND METHODS OF USE THEREOF | CYP11B1, PYGB, CYP11B2 | FAAH 2125/4885JAK3 1614/4885BTK 4785/4885 |
| US-12590096-B2 | Imidazo[2,1-f][1,2,4]triazin-4-amine as TLR8 agonists | TLR8, TLR7, TLR1 | FAAH 2294/4885JAK3 1229/4885BTK 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.