Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 3/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679943 | 0.91 | KMT2A (0.40) | HSPB1CRHBPCRHR2SMN1; SMN2NPSR1 | |
| SCHEMBL23086263 | 0.91 | MAPT (0.42) | CRHBPCRHR2SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL22966278 | 0.90 | SMN1; SMN2 (0.42) | HSPB1CRHBPCRHR2SMN1; SMN2NPSR1 | |
| SCHEMBL22966233 | 0.90 | TDP1 (0.48) | CRHBPCRHR2SMN1; SMN2NPSR1CYP1A2 | |
| SCHEMBL28701917 | 0.87 | MERTK (0.48) | CRHBPCRHR2SMN1; SMN2NPSR1CYP1A2 | |
| SCHEMBL1679873 | 0.83 | MEN1 (0.40) | HSPB1CRHBPCRHR2SMN1; SMN2NPSR1 | |
| SCHEMBL22966261 | 0.83 | SMN1; SMN2 (0.43) | CRHBPCRHR2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL22966220 | 0.83 | L3MBTL1 (0.51) | CRHBPCRHR2SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL22966231 | 0.82 | MAPT (0.43) | CRHBPCRHR2SMN1; SMN2NPSR1CYP1A2 | |
| SCHEMBL22966235 | 0.82 | MAPT (0.46) | CRHBPCRHR2SMN1; SMN2NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | Dongguan HEC Pesticides R&D Co., Ltd. (CN) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | NQO2, RDX, RIN1 | HSPB1 4061/4885CRHBP 3820/4885CRHR2 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.