Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966186 | 0.91 | HSPB1 (0.47) | MAPTCRHBPCRHR2TDP1ALDH1A1 | |
| SCHEMBL22966261 | 0.90 | SMN1; SMN2 (0.43) | MAPTCRHBPCRHR2TDP1ALDH1A1 | |
| SCHEMBL22966278 | 0.90 | SMN1; SMN2 (0.42) | MAPTCRHBPCRHR2TDP1ALDH1A1 | |
| SCHEMBL22966233 | 0.90 | TDP1 (0.48) | MAPTCRHBPCRHR2TDP1ALDH1A1 | |
| SCHEMBL1679943 | 0.89 | KMT2A (0.40) | MAPTCRHBPCRHR2TDP1ALDH1A1 | |
| SCHEMBL28701917 | 0.87 | MERTK (0.48) | MAPTCRHBPCRHR2TDP1ALDH1A1 | |
| SCHEMBL22966220 | 0.85 | L3MBTL1 (0.51) | CRHBPCRHR2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22966235 | 0.82 | MAPT (0.46) | MAPTCRHBPCRHR2TDP1ALDH1A1 | |
| SCHEMBL22966231 | 0.82 | MAPT (0.43) | MAPTCRHBPCRHR2TDP1ALDH1A1 | |
| SCHEMBL23086255 | 0.81 | KDM4E (0.42) | MAPTTDP1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790864-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | Dongguan Hec Pesticides R&D Co., Ltd. (CN) | 2021-03-17 | — | — | EP | disclosed |