Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23086263 | 0.90 | MAPT (0.42) | SMN1; SMN2RAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL22966231 | 0.88 | MAPT (0.43) | SMN1; SMN2RAB9AALDH1A1TDP1CRHBP | |
| SCHEMBL22966235 | 0.88 | MAPT (0.46) | SMN1; SMN2KDM4EPOLBALDH1A1TDP1 | |
| SCHEMBL22966220 | 0.84 | L3MBTL1 (0.51) | SMN1; SMN2RAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL22966186 | 0.83 | HSPB1 (0.47) | SMN1; SMN2RAB9AALDH1A1TDP1CRHBP | |
| SCHEMBL22966233 | 0.82 | TDP1 (0.48) | SMN1; SMN2POLBALDH1A1TDP1CRHBP | |
| SCHEMBL22966278 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9APOLBALDH1A1TDP1 | |
| SCHEMBL22966284 | 0.82 | KDM4E (0.46) | SMN1; SMN2KDM4EPOLBALDH1A1MAPT | |
| SCHEMBL1679943 | 0.81 | KMT2A (0.40) | SMN1; SMN2ALDH1A1TDP1CRHBPCRHR2 | |
| SCHEMBL28701917 | 0.80 | MERTK (0.48) | SMN1; SMN2RAB9AALDH1A1TDP1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | Dongguan HEC Pesticides R&D Co., Ltd. (CN) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040041-A1 | QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF | NQO2, RDX, RIN1 | SMN1; SMN2 2216/4885RAB9A 73/4885KDM4E 2863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.