Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24094128 | 0.89 | PLG (0.34) | GAACHEK2HSD17B10RAB9ANPC1 | |
| SCHEMBL24610274 | 0.88 | HTR1D (0.32) | GAAHSD17B10RAB9ANPC1TP53 | |
| SCHEMBL24094118 | 0.86 | PRMT5 (0.41) | MAPTGAAMEN1KMT2ACHEK2 | |
| SCHEMBL24094240 | 0.84 | NPBWR1 (0.35) | MAPTTSHRKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL24610300 | 0.82 | JAK2 (0.34) | CHEK2SMN1; SMN2 | |
| SCHEMBL24094286 | 0.82 | IKBKE (0.36) | ALDH1A1MAPTNPSR1TSHRCHEK2 | |
| SCHEMBL22967237 | 0.81 | CYP1A2 (0.43) | ALDH1A1MAPTKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL24610309 | 0.81 | IKBKE (0.39) | CHEK2TBK1 | |
| SCHEMBL22967056 | 0.80 | ADORA2A (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL22967060 | 0.80 | ADORA2A (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743420-B1 | HETEROCYCLYLAMINO-SUBSTITUTED TRIAZOLES AS MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | REDX PHARMA PLC (GB) | 2021-12-15 | — | — | EP | disclosed |