SCHEMBL22972766

SCHEMBL22972766

CCOc1c(-c2ccc(C(=O)O)cc2)cc(-c2ccc(C(=O)O)cc2)cc1-c1cc(-c2ccc(C(=O)O)cc2)cc(-c2ccc(C(=O)O)cc2)c1OCC

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RXRA P19793 4/20 0.56
RXRB P28702 3/20 0.56
SRD5A2 P31213 1/20 0.51
HCRTR1 O43613 1/20 0.49
HCRTR2 O43614 1/20 0.49
RARB P10826 4/20 0.47
RARG P13631 1/20 0.47
EGFR P00533 1/20 0.47
PLA2G4B P0C869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29908909 1.00 RXRA (0.56) RXRARXRBSRD5A2HCRTR1HCRTR2
SCHEMBL16749640 0.82 RARB (0.68) RARBPLA2G4B
SCHEMBL16749635 0.81 MAPT (0.54) RXRARXRBSRD5A2RARBRARG
SCHEMBL21182646 0.80 RXRA (0.64) RXRARXRBRARBRARGEGFR
SCHEMBL25125396 0.79 TSHR (0.57) RXRARXRBSRD5A2HCRTR1HCRTR2
SCHEMBL7972144 0.78 RXRA (0.63) RXRARXRBHCRTR1HCRTR2RARB
SCHEMBL202683 0.76 PLA2G4B (0.74) RXRARXRBSRD5A2HCRTR1HCRTR2
SCHEMBL1721733 0.76 TSHR (0.62) RXRARXRBSRD5A2HCRTR1HCRTR2
SCHEMBL1568239 0.76 RXRA (0.54) RXRARXRBHCRTR1HCRTR2EGFR
SCHEMBL16749637 0.74 RXRA (0.66) RXRARXRBRARBRARGEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629639-B2 Spacer for a spiral wound membrane EVOVE LTD (GB) 2026-05-19 US disclosed
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 EP disclosed
US-20240157304-A1 SPACER FOR A SPIRAL WOUND MEMBRANE EVOVE LTD (GB) 2024-05-16 US disclosed
US-20240149223-A1 MEMBRANE DEVICE EVOVE LTD (GB) 2024-05-09 US disclosed
EP-4304765-A1 SPACER FOR A SPIRAL WOUND MEMBRANE Evove Ltd (GB) 2024-01-17 EP disclosed
EP-4304766-A1 MEMBRANE DEVICE Evove Ltd (GB) 2024-01-17 EP disclosed
WO-2022189785-A1 SPACER FOR A SPIRAL WOUND MEMBRANE EVOVE LTD (GB) 2022-09-15 WO disclosed
EP-3774001-A1 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2021-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629639-B2 Spacer for a spiral wound membrane AQP1, AQP3, AQP4 RXRA 3105/4885RXRB 3668/4885SRD5A2 2250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.