Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22972833 | 0.82 | PTGS1 (0.43) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL22972834 | 0.82 | PTGS1 (0.43) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL22972828 | 0.82 | MGLL (0.36) | OPRM1OPRD1OPRK1AKT1PTGS1 | |
| SCHEMBL22972829 | 0.82 | MGLL (0.36) | OPRM1OPRD1OPRK1AKT1PTGS1 | |
| SCHEMBL17739813 | 0.76 | OPRM1 (0.50) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL24045356 | 0.74 | OPRM1 (0.46) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL20087382 | 0.74 | PTGS1 (0.54) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL8549460 | 0.74 | EPHX1 (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8549463 | 0.74 | EPHX1 (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8544801 | 0.72 | KEAP1 (0.35) | MTNR1APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221698-B1 | POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF | Global Life Sciences Solutions Operations UK Ltd (GB) | 2021-02-17 | — | — | EP | claimed |