Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 5/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22972828 | 1.00 | MGLL (0.36) | MGLLAKT1ALDH1A1CYP1A2HPGD | |
| SCHEMBL22972832 | 0.82 | OPRM1 (0.43) | MGLLAKT1ALDH1A1HPGDPTGS1 | |
| SCHEMBL4834215 | 0.80 | ACHE (0.36) | ALDH1A1ACHE | |
| SCHEMBL22972833 | 0.78 | PTGS1 (0.43) | MGLLALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL22972834 | 0.78 | PTGS1 (0.43) | MGLLALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL13799114 | 0.76 | ACHE (0.60) | MGLLPTGS1PTGS2ACHE | |
| SCHEMBL4141287 | 0.75 | MGLL (0.47) | MGLLAKT1ALDH1A1CYP1A2HPGD | |
| SCHEMBL17767404 | 0.74 | MGLL (0.38) | MGLLAKT1ALDH1A1CYP1A2HPGD | |
| SCHEMBL29185 | 0.74 | ACHE (0.54) | ACHE | |
| SCHEMBL13811888 | 0.73 | MGLL (0.42) | MGLLAKT1ALDH1A1HPGDPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221698-B1 | POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF | Global Life Sciences Solutions Operations UK Ltd (GB) | 2021-02-17 | — | — | EP | claimed |