Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 2/20 | 0.35 |
| ▸ | PGK2 | P07205 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889192 | 0.82 | MMP8 (0.44) | ACP3LAP3ANPEPPGK1PGK2 | |
| SCHEMBL8341042 | 0.80 | LAP3 (0.60) | ACP3LAP3ANPEPTAAR1SLC6A2 | |
| SCHEMBL21408350 | 0.75 | POLB (0.39) | LMNA | |
| SCHEMBL29108968 | 0.75 | LAP3 (0.35) | ACP3LAP3ANPEPPTPRCCES2 | |
| SCHEMBL3364798 | 0.73 | PGK1 (0.55) | ACP3CES2CES1PGK1PGK2 | |
| SCHEMBL1305821 | 0.72 | PTGS1 (0.47) | LMNAALBESR1ALOX5RARB | |
| SCHEMBL22973753 | 0.72 | ACP3 (0.35) | ACP3LAP3ANPEPPTPRCALOX5 | |
| SCHEMBL4632775 | 0.71 | ESR1 (0.42) | CES2CES1LMNAALBESR1 | |
| SCHEMBL22973715 | 0.69 | GRIN2D (0.47) | CES2CES1 | |
| SCHEMBL4056413 | 0.69 | TRPA1 (0.42) | CES2CES1TAAR1SLC6A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778612-A1 | PHOSPHATE DERIVATIVES AND USE THEREOF | Zhu, Qing (CN) | 2021-02-17 | — | — | EP | disclosed |