SCHEMBL22975005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23917435	0.92	ROCK1 (0.40)	NUDT1EEDROCK1CHRM2CHRM4
	SCHEMBL23908721	0.87	EED (0.38)	NUDT1EEDROCK1CHRM2CHRM4
	SCHEMBL29478502	0.79	ROCK1 (0.51)	NUDT1ROCK1OPRM1SMN1; SMN2SIGMAR1
	SCHEMBL693233	0.79	ROCK1 (0.51)	NUDT1ROCK1OPRM1SMN1; SMN2SIGMAR1
	SCHEMBL23917713	0.78	SPR (0.49)	NUDT1EEDROCK1AKT1PIK3CA
	SCHEMBL618870	0.74	OPRM1 (0.48)	ROCK1OPRM1SMN1; SMN2SIGMAR1L3MBTL1
	SCHEMBL23917712	0.73	ROCK1 (0.39)	NUDT1EEDROCK1OPRM1AKT1
	SCHEMBL17374725	0.72	OPRM1 (0.47)	NUDT1EEDROCK1OPRM1AKT1
	SCHEMBL23908719	0.71	ROCK1 (0.43)	NUDT1ROCK1OPRM1AKT1PIK3CA
	SCHEMBL23917695	0.71	ROCK1 (0.40)	NUDT1EEDROCK1OPRM1AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.