Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR known ✓ | P35968 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.61 |
| ▸ | BCL2 | P10415 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833241 | 0.96 | HSPD1 (0.66) | HSPD1HSPE1BCL2KMT2AMEN1 | |
| SCHEMBL526907 | 0.96 | HSPD1 (0.66) | HSPD1HSPE1BCL2KMT2AMEN1 | |
| SCHEMBL229763 | 0.94 | HSPD1 (0.68) | HSPD1HSPE1BCL2KMT2AMEN1 | |
| SCHEMBL29474808 | 0.94 | HSPD1 (0.68) | HSPD1HSPE1BCL2KMT2AMEN1 | |
| SCHEMBL5805742 | 0.93 | HSPD1 (0.66) | HSPD1HSPE1BCL2KMT2AMEN1 | |
| Phosphoric Acid SCHEMBL7515153 | 0.90 | HSPD1 (0.59) | HSPD1HSPE1BCL2KMT2AMEN1 | |
| SCHEMBL28497138 | 0.78 | HSPD1 (0.58) | HSPD1HSPE1BCL2KMT2AMEN1 | |
| SCHEMBL22767660 | 0.78 | HSPD1 (0.66) | HSPD1HSPE1BCL2KMT2AMEN1 | |
| SCHEMBL3441192 | 0.77 | HSPD1 (0.60) | HSPD1HSPE1BCL2KMT2AMEN1 | |
| Metabromsalan SCHEMBL1162534 | 0.76 | HSPD1 (1.00) | HSPD1HSPE1BCL2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171084-A1 | ZINC CONTAINING DENTIFRICE COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061092-A1 | ZINC CONTAINING DENTIFRICE COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 2000-10-19 | — | — | WO | disclosed |