Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22976791 | 1.00 | ADRB2 (0.53) | ADRB2ADRB1ADRB3KMT2ASLC6A2 | |
| SCHEMBL22976871 | 0.85 | KMT2A (0.58) | ADRB2ADRB1ADRB3KMT2ASLC6A2 | |
| SCHEMBL21215918 | 0.85 | KMT2A (0.58) | ADRB2ADRB1ADRB3KMT2ASLC6A2 | |
| SCHEMBL12849131 | 0.84 | KMT2A (0.56) | ADRB2ADRB1ADRB3KMT2ASLC6A2 | |
| SCHEMBL16358433 | 0.84 | ADRB2 (0.59) | ADRB2ADRB1ADRB3KMT2ASLC6A2 | |
| SCHEMBL21216016 | 0.81 | KMT2A (0.56) | ADRB2ADRB1ADRB3KMT2ASLC6A2 | |
| SCHEMBL25119571 | 0.81 | MAPT (0.56) | ADRB2ADRB1ADRB3KMT2ASLC6A2 | |
| SCHEMBL21198582 | 0.80 | PLA2G4B (0.56) | LMNAMAPTALDH1A1NR4A1NR4A2 | |
| SCHEMBL21198583 | 0.80 | PLA2G4B (0.56) | LMNAMAPTALDH1A1NR4A1NR4A2 | |
| SCHEMBL20830746 | 0.79 | KMT2A (0.61) | ADRB2ADRB1ADRB3KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453657-B2 | Compounds for the treatment of parasitic infections | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-09-27 | — | — | US | disclosed |
| US-20210047299-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF PARASITIC INFECTIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11453657-B2 | Compounds for the treatment of parasitic infections | PIGO, SGMS2, ABCB11 | ADRB2 2729/4885ADRB1 2855/4885ADRB3 2160/4885 |
| US-20210047299-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF PARASITIC INFECTIONS | PIGO, ENPP2, THPO | ADRB2 2811/4885ADRB1 2852/4885ADRB3 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.