Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22976065 | 0.82 | ALDH1A1 (0.51) | NAMPTKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL952140 | 0.82 | L3MBTL1 (0.50) | NAMPTKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL22987577 | 0.80 | GAA (0.59) | NAMPTKDM4EALDH1A1NPC1P2RX7 | |
| SCHEMBL954236 | 0.80 | L3MBTL1 (0.56) | NAMPTKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL334433 | 0.80 | NAMPT (0.54) | NAMPTKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL841237 | 0.79 | ALDH1A1 (0.51) | NAMPTKDM4EALDH1A1NPC1LMNA | |
| Hydrochloric Acid SCHEMBL29450056 | 0.79 | GAA (0.58) | NAMPTKDM4EALDH1A1NPC1P2RX7 | |
| SCHEMBL23273647 | 0.76 | L3MBTL1 (0.47) | NAMPTKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL952167 | 0.75 | SMN1; SMN2 (0.45) | NAMPTKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL22979652 | 0.75 | P2RX7 (0.42) | NAMPTKDM4EALDH1A1NPC1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |