Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954236 | 0.85 | L3MBTL1 (0.56) | NAMPTL3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL952140 | 0.83 | L3MBTL1 (0.50) | NAMPTL3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL22976065 | 0.83 | ALDH1A1 (0.51) | NAMPTL3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6155749 | 0.80 | ACHE (0.40) | NAMPTL3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL841237 | 0.80 | ALDH1A1 (0.51) | NAMPTL3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL23273647 | 0.80 | L3MBTL1 (0.47) | NAMPTL3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL22979377 | 0.80 | NAMPT (0.57) | NAMPTL3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14490958 | 0.79 | KDM4E (0.42) | NAMPTL3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL3759226 | 0.79 | NAMPT (0.43) | NAMPTL3MBTL1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL17454362 | 0.79 | NAMPT (0.37) | NAMPTL3MBTL1SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1985620-A1 | 10a-AZALIDE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | NAMPT 3116/4885L3MBTL1 2853/4885SMN1; SMN2 3120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.