SCHEMBL229796

SCHEMBL229796

CCOC(OCC)(OCC)O[SiH2]c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32
KCNH2 Q12809 1/20 0.32
LTA4H P09960 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TP53 P04637 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229739 0.77 CA4 (0.33)
SCHEMBL225534 0.77 ALDH1A1 (0.30)
SCHEMBL4267333 0.75 L3MBTL1 (0.33) L3MBTL1MEN1KMT2ATP53
SCHEMBL4269703 0.73 RIPK1 (0.33) MEN1KMT2ATP53
SCHEMBL4277972 0.72 MEN1 (0.32) L3MBTL1MEN1KMT2ATP53
SCHEMBL715568 0.72 MAPK1 (0.37)
SCHEMBL703521 0.72 LTA4H (0.37) L3MBTL1KCNH2LTA4HMEN1KMT2A
SCHEMBL28470623 0.71 KCNH2 (0.37) L3MBTL1KCNH2LTA4HMEN1KMT2A
SCHEMBL11799550 0.71 ALDH1A1 (0.38) MEN1KMT2A
SCHEMBL19646666 0.71 RIPK1 (0.31) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623958-B2 Oil-in-water silicone emulsion composition DOW CORNING TORAY CO. LTD. (JP) 2014-01-07 US disclosed
EP-2406323-B1 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO LTD (JP) 2013-07-24 EP disclosed
EP-2406322-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
EP-2406323-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
US-20120004354-A1 Oil-In-Water Silicone Emulsion Composition DOW TORAY CO., LTD. (JP) 2012-01-05 US disclosed
US-20110319557-A1 Oil-In-Water Silicone Emulsion Composition DOW CORNING TORAY CO., LTD. (JP) 2011-12-29 US disclosed
WO-2010104186-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed
WO-2010104185-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed