Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.69 |
| ▸ | CTSS | P25774 | 4/20 | 0.65 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.60 |
| ▸ | KLK7 | P49862 | 2/20 | 0.60 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22980203 | 1.00 | PPARA (0.69) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL9743961 | 0.94 | PPARA (0.74) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL2948481 | 0.91 | PPARA (0.74) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL2948482 | 0.91 | PPARA (0.74) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL5249102 | 0.91 | PPARA (0.74) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL7518373 | 0.89 | PPARA (0.74) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL19853661 | 0.89 | PPARA (0.74) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL1132901 | 0.86 | PPARA (0.90) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL17051 | 0.86 | PPARA (0.90) | PPARACTSSPPARGKLK5KLK7 | |
| SCHEMBL828674 | 0.86 | PPARA (0.90) | PPARACTSSPPARGKLK5KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010329-B9 | DEUTERATED COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LTD (GB) | 2023-10-04 | — | — | EP | disclosed |
| EP-4010329-B1 | DEUTERATED COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LTD (GB) | 2023-06-07 | — | — | EP | disclosed |
| US-20220259174-A1 | DEUTERATED COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2022-08-18 | — | — | US | disclosed |
| CN-114846003-A | Deuterated compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2022-08-02 | — | — | CN | disclosed |
| EP-4010329-A1 | DEUTERATED COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Artios Pharma Limited (GB) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021028670-A1 | DEUTERATED COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220259174-A1 | DEUTERATED COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | SDHA, SDHB, HCCS | PPARA 342/4885CTSS 2770/4885PPARG 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.