Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27348192 | 0.82 | KHK (0.36) | KHKL3MBTL1ALDH1A1GLAHTT | |
| SCHEMBL11723001 | 0.79 | HTT (0.42) | L3MBTL1ALDH1A1GLAHTTMAPK1 | |
| SCHEMBL6627580 | 0.76 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1GLAHTTMAPK1 | |
| SCHEMBL4068543 | 0.76 | L3MBTL1 (0.33) | KHKL3MBTL1ALDH1A1GLAHTT | |
| SCHEMBL4193505 | 0.76 | HTT (0.38) | KHKL3MBTL1ALDH1A1GLAHTT | |
| SCHEMBL29409508 | 0.75 | KDM4E (0.40) | L3MBTL1ALDH1A1GLAHTTMAPK1 | |
| SCHEMBL1624009 | 0.75 | KDM4E (0.40) | L3MBTL1ALDH1A1GLAHTTMAPK1 | |
| SCHEMBL9987538 | 0.75 | L3MBTL1 (0.33) | KHKL3MBTL1ALDH1A1GLAHTT | |
| SCHEMBL1624060 | 0.75 | L3MBTL1 (0.33) | KHKL3MBTL1ALDH1A1GLAHTT | |
| SCHEMBL4193500 | 0.72 | L3MBTL1 (0.36) | KHKL3MBTL1ALDH1A1GLAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010080-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Artios Pharma Limited (GB) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021028643-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |