Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22980966 | 0.82 | KHK (0.34) | KHKL3MBTL1ALDH1A1HTTGLA | |
| SCHEMBL11723001 | 0.81 | HTT (0.42) | L3MBTL1ALDH1A1HTTGLAMAPK1 | |
| SCHEMBL6627580 | 0.79 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1HTTGLAMAPK1 | |
| SCHEMBL4068543 | 0.79 | L3MBTL1 (0.33) | KHKL3MBTL1ALDH1A1HTTGLA | |
| SCHEMBL4193505 | 0.78 | HTT (0.38) | KHKL3MBTL1ALDH1A1HTTGLA | |
| SCHEMBL1624060 | 0.77 | L3MBTL1 (0.33) | KHKL3MBTL1ALDH1A1HTTGLA | |
| SCHEMBL9987538 | 0.77 | L3MBTL1 (0.33) | KHKL3MBTL1ALDH1A1HTTGLA | |
| SCHEMBL21154750 | 0.75 | TAAR1 (0.38) | L3MBTL1ALDH1A1HTTGLAKDM4E | |
| SCHEMBL7600961 | 0.75 | TRPV4 (0.43) | KHKL3MBTL1ALDH1A1HTTGLA | |
| SCHEMBL30402943 | 0.74 | L3MBTL1 (0.40) | KHKL3MBTL1ALDH1A1HTTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630114-A1 | NEW CYANOPYRIDINE KHK INHIBITOR COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121183-A1 | NEW CYANOPYRIDINE KHK INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024121183-A1 | NEW CYANOPYRIDINE KHK INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-06-13 | — | — | WO | disclosed |