Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848546 | 1.00 | DGAT1 (0.48) | DGAT1SOAT1KCNH2ASIC3PDE3B | |
| SCHEMBL29848592 | 0.88 | NOTUM (0.49) | DGAT1SOAT1KCNH2PDE3BPDE3A | |
| SCHEMBL29848643 | 0.83 | CCNA2 (0.53) | DGAT1SOAT1KCNH2ASIC3PDE3B | |
| SCHEMBL31289499 | 0.80 | DGAT1 (0.58) | DGAT1SOAT1KCNH2TERTSMN1; SMN2 | |
| SCHEMBL29848634 | 0.79 | DGAT1 (0.56) | DGAT1SOAT1KCNH2TERTSMN1; SMN2 | |
| SCHEMBL29959068 | 0.78 | MAPT (0.59) | ASIC3PDE3BPDE3ASMN1; SMN2ALDH1A1 | |
| SCHEMBL880662 | 0.78 | MAPT (0.59) | ASIC3PDE3BPDE3ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22981809 | 0.76 | MEN1 (0.52) | SMN1; SMN2ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29848557 | 0.76 | MEN1 (0.52) | SMN1; SMN2ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL23011272 | 0.75 | NR1H2 (0.52) | PDE3BPDE3ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021029665-A1 | NOVEL IMIDAZOLE DERIVATIVE EXPRESSING FLT3 INHIBITORY ACTIVITY, AND USE THEREOF | 한양대학교 에리카산학협력단 | 2021-02-18 | — | — | WO | disclosed |
| WO-2021029665-A1 | NOVEL IMIDAZOLE DERIVATIVE EXPRESSING FLT3 INHIBITORY ACTIVITY, AND USE THEREOF | 한양대학교 에리카산학협력단 | 2021-02-18 | — | — | WO | disclosed |