Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND3 | P30281 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 8/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848496 | 0.89 | SLC6A9 (0.49) | NPBWR1PDE3BPDE3ADGAT1SOAT1 | |
| SCHEMBL22982108 | 0.83 | DGAT1 (0.48) | CCNA2CDK2CCNA1PIM1CDK4 | |
| SCHEMBL29848546 | 0.83 | DGAT1 (0.48) | CCNA2CDK2CCNA1PIM1CDK4 | |
| SCHEMBL22982443 | 0.81 | KCNH2 (0.52) | NPBWR1DGAT1SOAT1KCNH2MAPT | |
| SCHEMBL853678 | 0.80 | CCNA2 (0.58) | CCNA2CDK2CCNA1PIM1CDK4 | |
| SCHEMBL29848847 | 0.79 | NPBWR1 (0.57) | NPBWR1MAPTHTTRAB9ANPC1 | |
| SCHEMBL29848499 | 0.77 | NPBWR1 (0.44) | NPBWR1MAPTHTTRAB9ANPC1 | |
| SCHEMBL5564066 | 0.76 | LMNA (0.58) | CCNA2CDK2CCNA1PIM1CDK4 | |
| SCHEMBL4258177 | 0.76 | NPBWR1 (0.58) | NPBWR1MAPTHTTRAB9ANPC1 | |
| SCHEMBL10127582 | 0.73 | SIRT6 (0.56) | CCNA2CDK2CCNA1PIM1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473278-B2 | Imidazole derivative expressing FLT3 inhibitory activity, and use thereof | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2025-11-18 | — | — | US | disclosed |
| US-20220315573-A1 | Novel Imidazole Derivative Expressing FLT3 Inhibitory Activity, and Use Thereof | Industry-University Cooperation Foundation Hangyang University Erica Campus (KR) | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315573-A1 | Novel Imidazole Derivative Expressing FLT3 Inhibitory Activity, and Use Thereof | FLT3, FLI1, MCL1 | CCNA2 3368/4885CDK2 969/4885CCNA1 3334/4885 |
| US-12473278-B2 | Imidazole derivative expressing FLT3 inhibitory activity, and use thereof | FLT3, FLI1, MCL1 | CCNA2 3653/4885CDK2 960/4885CCNA1 3532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.