SCHEMBL22982497

SCHEMBL22982497

C1=Cc2cc3ccccc3cc2[C]1Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
CALM1 P0DP23 1/20 0.39
BCL2 P10415 1/20 0.34
BCL2L1 Q07817 1/20 0.34
ALOX5 P09917 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
LTA4H P09960 1/20 0.33
IDH1 O75874 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22982469 0.84 KCNH2 (0.37) CYP11B1CYP11B2ALOX5CYP1A2CYP2D6
SCHEMBL22982022 0.77 CYP2A6 (0.41) CYP1A2ALDH1A1TP53HPGDTSHR
SCHEMBL216992 0.76 CALM1 (0.46) CALM1BCL2BCL2L1CYP1A2CYP2D6
SCHEMBL28762178 0.76 PARP11 (0.36) CALM1LTA4HIDH1TSHR
SCHEMBL22982711 0.76 NPC1 (0.35) CALM1BCL2BCL2L1ALDH1A1KMT2A
SCHEMBL28804530 0.75 NPC1 (0.35) CALM1BCL2BCL2L1ALDH1A1KMT2A
SCHEMBL22982410 0.74 RIPK1 (0.33) CYP1A2ALDH1A1TP53HPGDTSHR
SCHEMBL22982483 0.74 CYP1A2 (0.34) CYP1A2ALDH1A1TP53HPGDTSHR
SCHEMBL22982567 0.74
SCHEMBL22982020 0.73 HTR2A (0.36) ALDH1A1TP53HPGDTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11661465-B2 Dimer selective metallocene catalysts, non-aromatic hydrocarbon soluble activators, and processes to produce poly alpha-olefin oligmers therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-30 US disclosed
CN-114845980-A Dimer-selective metallocene catalyst, non-aromatic hydrocarbon soluble activator and method for preparing poly alpha-olefin oligomer using the same 埃克森美孚化学专利公司 2022-08-02 CN disclosed
EP-4010385-A1 PROCESS TO PRODUCE LOW VISCOSITY POLYALPHAOLEFINS USING NON-AROMATIC-HYDROCARBON SOLUBLE ACTIVATORS ExxonMobil Chemical Patents Inc. (US) 2022-06-15 EP disclosed
CN-114502521-A Process for producing low viscosity polyalphaolefins using non-aromatic hydrocarbon soluble activators 埃克森美孚化学专利公司 2022-05-13 CN disclosed
WO-2021086926-A1 DIMER SELECTIVE METALLOCENE CATALYSTS, NON-AROMATIC HYDROCARBON SOLUBLE ACTIVATORS, AND PROCESSES TO PRODUCE POLY ALPHA-OLEFIN OLIGMERS THEREWITH EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-05-06 WO disclosed
US-20210122859-A1 Dimer Selective Metallocene Catalysts, Non-Aromatic Hydrocarbon Soluble Activators, And Processes To Produce Poly Alpha-Olefin Oligmers Therewith EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-04-29 US disclosed
WO-2021030045-A1 PROCESS TO PRODUCE LOW VISCOSITY POLYALPHAOLEFINS USING NON-AROMATIC-HYDROCARBON SOLUBLE ACTIVATORS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11661465-B2 Dimer selective metallocene catalysts, non-aromatic hydrocarbon soluble activators, and processes to produce poly alpha-olefin oligmers therewith NONO, TPR, ZNF787 CYP11B1 1118/4885CYP11B2 1391/4885CALM1 4120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.