Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483872 | 0.79 | MIF (0.34) | MIFLMNA | |
| SCHEMBL10959509 | 0.74 | CYP2C19 (0.30) | — | |
| SCHEMBL5182817 | 0.72 | MIF (0.34) | CYP2D6MIFLMNATSHR | |
| SCHEMBL8283160 | 0.69 | MIF (0.37) | MIF | |
| SCHEMBL7463991 | 0.68 | MIF (0.36) | CYP2D6MIFLMNA | |
| SCHEMBL4847089 | 0.67 | RIPK1 (0.36) | CYP2D6SRCMIFLMNAMAPK1 | |
| SCHEMBL5694065 | 0.66 | MIF (0.31) | MIF | |
| SCHEMBL5182810 | 0.66 | CNR1 (0.42) | CYP2D6LMNA | |
| SCHEMBL20146 | 0.65 | MIF (0.40) | CYP2D6SRCMIFLMNAMAPK1 | |
| SCHEMBL43325 | 0.65 | SRC (0.42) | CYP2D6SRCMIFLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190535-A1 | PROCESS FOR PREPARING POLYAROMATIC POLYISOCYANATE COMPOSITIONS | HUNTSMAN INTERNATIONAL LLC (US) | 2011-08-04 | — | — | US | disclosed |
| EP-2183295-A1 | PROCESS FOR PREPARING POLYAROMATIC POLYISOCYANATE COMPOSITIONS | Huntsman International LLC (US) | 2010-05-12 | — | — | EP | disclosed |
| US-20090264551-A1 | Photocurable fixture for orthopedic surgery background of the invention | ALCARE CO., LTD. | 2009-10-22 | — | — | US | disclosed |
| WO-2009024407-A1 | PROCESS FOR PREPARING POLYAROMATIC POLYISOCYANATE COMPOSITIONS | HUNTSMAN INTERNATIONAL LLC (US) | 2009-02-26 | — | — | WO | disclosed |
| EP-0508183-B1 | Cartridge for chemical fixing engineering | BASF AG (DE) | 1995-06-07 | — | — | EP | disclosed |
| EP-0527410-A2 | Impact modified vinylester urethane resins | BASF Aktiengesellschaft (DE) | 1993-02-17 | — | — | EP | disclosed |
| EP-0508183-A1 | Cartridge for chemical fixing engineering | BASF Aktiengesellschaft (DE) | 1992-10-14 | — | — | EP | disclosed |
| EP-0507152-A2 | Tubular construction materials from fibre-laminates | BASF Aktiengesellschaft (DE) | 1992-10-07 | — | — | EP | disclosed |
| EP-0458028-A1 | Prepreg for high performance-composites | BASF Aktiengesellschaft (DE) | 1991-11-27 | — | — | EP | disclosed |
| EP-0454983-A1 | Leaf springs of fibre composite materials | BASF Aktiengesellschaft (DE) | 1991-11-06 | — | — | EP | disclosed |
| EP-0162346-B1 | TRIISOCYANATES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE IN THE MANUFACTURE OF POLYURETHANES | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| US-4613687-A | POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-23 | — | — | US | disclosed |
| US-4603189-A | Triisocyanates and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-29 | — | — | US | disclosed |
| EP-0162346-A1 | Triisocyanates, process for their production, and their use in the manufacture of polyurethanes | BAYER AG (DE) | 1985-11-27 | — | — | EP | disclosed |
| EP-0046917-B1 | POLYISOCYANATE MIXTURES OF THE DIPHENYLMETHANE CLASS, AS WELL AS THEIR USE AS SYNTHESIS COMPONENTS IN THE MANUFACTURE OF POLYURETHANES BY THE ISOCYANATE-POLYADDITION PROCESS | BAYER AG (DE) | 1983-12-07 | — | — | EP | disclosed |
| EP-0046917-A1 | Polyisocyanate mixtures of the diphenylmethane class, as well as their use as synthesis components in the manufacture of polyurethanes by the isocyanate-polyaddition process | BAYER AG (DE) | 1982-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190535-A1 | PROCESS FOR PREPARING POLYAROMATIC POLYISOCYANATE COMPOSITIONS | MAOA, DDC, MAOB | CYP2D6 684/4885SRC 3651/4885MIF 3405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.