Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | CSGALNACT1 | Q8TDX6 | 13/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293643 | 0.85 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2298415 | 0.82 | MEN1 (0.58) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2293726 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2295116 | 0.78 | MEN1 (0.58) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2295109 | 0.78 | MEN1 (0.58) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2297791 | 0.78 | RAB9A (0.58) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2298617 | 0.78 | RAB9A (0.57) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2294246 | 0.77 | CSGALNACT1 (0.68) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2294252 | 0.77 | CSGALNACT1 (0.68) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL2298410 | 0.77 | CSGALNACT1 (0.56) | SMN1; SMN2KDM4ERAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110196002-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED. | 2011-08-11 | — | — | US | claimed |
| WO-2010023609-A1 | OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196002-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | DGAT1, DGAT2, DLAT | SMN1; SMN2 4532/4885KDM4E 4272/4885RAB9A 3753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.