Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28544504 | 0.84 | VCP (0.42) | ADORA2AADORA1ADORA3ALDH1A1KDM4E | |
| SCHEMBL20576178 | 0.84 | VCP (0.42) | ADORA2AADORA1ADORA3ALDH1A1KDM4E | |
| SCHEMBL29389343 | 0.82 | PIM1 (0.39) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL28685777 | 0.79 | BTK (0.40) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL28689738 | 0.74 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL28689734 | 0.74 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL20576121 | 0.71 | ADORA3 (0.42) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30321134 | 0.71 | TDP1 (0.44) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL28703145 | 0.68 | ADORA3 (0.42) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL25279114 | 0.67 | FFAR4 (0.44) | ALDH1A1NPSR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927118-B2 | Inhibitors of influenza virus replication and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927118-B2 | Inhibitors of influenza virus replication and uses thereof | EIF2AK2, POLRMT, ZC3HAV1 | ADORA2A 2174/4885ADORA1 2417/4885ADORA3 2651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.